Deep brain stimulation (DBS) is an effective treatment for neurological movement disorders such as those that occur in Parkinson’s disease. However, DBS is a treatment for which there is room for improvement. In an effort to facilitate the work of surgeons as well as improve the surgical conditions of patients, DCClab is looking for non-invasive techniques to provide information about the position of the electrode in the brain during its final implantation. In the research group, several optical techniques are being explored, including Raman spectroscopy. Indeed, this non-invasive spectroscopy technique allows to obtain information on the molecular composition of a medium.
In the context of my master’s project, I aim to determine the experimental conditions that allow the differentiation of certain brain tissues using Raman spectroscopy. In order to do so, an optical system has been designed, followed by the design of a Python algorithm to manage, process and analyze the data.